SCHEMBL790752

SCHEMBL790752

[CH]1CCC2NCCCC2C1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPAS1 Q99814 1/20 0.36
MBTD1 Q05BQ5 1/20 0.35
L3MBTL3 Q96JM7 1/20 0.35
DRD2 P14416 1/20 0.31
HRH4 Q9H3N8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL944517 0.86
SCHEMBL21722574 0.82 EPAS1 (0.36) EPAS1MBTD1L3MBTL3DRD2HRH4
SCHEMBL5939379 0.81 EPAS1 (0.38) EPAS1MBTD1L3MBTL3HRH4
SCHEMBL5939367 0.81 EPAS1 (0.38) EPAS1MBTD1L3MBTL3HRH4
SCHEMBL5939649 0.81 EPAS1 (0.38) EPAS1MBTD1L3MBTL3HRH4
SCHEMBL5939656 0.81 EPAS1 (0.38) EPAS1MBTD1L3MBTL3HRH4
SCHEMBL90804 0.72 MBTD1 (0.44) EPAS1MBTD1L3MBTL3
SCHEMBL22915706 0.72
SCHEMBL13382602 0.72
SCHEMBL14621027 0.72 MBTD1 (0.44) EPAS1MBTD1L3MBTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024150146-A1 ENGINEERED KETOREDUCTASE POLYPEPTIDES NOVARTIS AG (CH) 2024-07-18 WO disclosed
US-12024595-B2 Polymer composition BASF SE (DE) 2024-07-02 US disclosed
US-20240182473-A1 COMPOUNDS USEFUL IN HIV THERAPY GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2024-06-06 US disclosed
EP-4365182-A1 GEMCITABINE ANTICANCER DERIVATIVE AND ANTICANCER PHARMACEUTICAL USE Ascentawits Pharmaceuticals, Ltd. (CN) 2024-05-08 EP disclosed
US-20240140970-A1 A DEUTERATED COMPOUND, AND PREPARATION METHOD AND USE THEREOF ASCENTAWITS PHARMACEUTICALS LTD (CN) 2024-05-02 US disclosed
CN-117941786-A Functional beverage and preparation method thereof 武汉市中心医院 2024-04-30 CN disclosed
CN-117956998-A Cancer patients treated for KRAS mutations 深圳艾欣达伟医药科技有限公司 2024-04-30 CN disclosed
CN-117918483-A Red rice fermented black rice flour and preparation method and application thereof 武汉市中心医院 2024-04-26 CN disclosed
EP-4342473-A2 COMPOUNDS USEFUL IN HIV THERAPY GlaxoSmithKline Intellectual Property Development Limited (GB) 2024-03-27 EP disclosed
US-20240051972-A1 Compounds Useful in HIV Therapy GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2024-02-15 US disclosed
EP-1853585-A1 3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID 5-AMINOPYRIDIN-2-YL ESTERS Novo Nordisk A/S (DK) 2007-11-14 EP disclosed
WO-2007125105-A2 BENZAMIDE GLUCOKINASE ACTIVATORS TRANSTECH PHARMA, INC. (US) 2007-11-08 WO disclosed
WO-2007125103-A2 BENZAMIDE GLUCOKINASE ACTIVATORS TRANSTECH PHARMA, INC. (US) 2007-11-08 WO disclosed
WO-2007110364-A1 BENZOTHIAZOLES HAVING HISTAMINE H3 RECEPTOR ACTIVITY HIGH POINT PHARMACEUTICALS, LLC (US) 2007-10-04 WO disclosed
WO-2007107550-A1 ADAMANTANE DERIVATIVES FOR THE TREATMENT OF THE METABOLIC SYNDROME HIGH POINT PHARMACEUTICALS, LLC (US) 2007-09-27 WO disclosed
WO-2007101864-A2 COMPOUNDS THAT MODULATE PPAR ACTIVITY, THEIR PREPARATION AND USE HIGH POINT PHARMACEUTICALS, LLC (US) 2007-09-13 WO disclosed
WO-2007071766-A2 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS TRANSTECH PHARMA (US) 2007-06-28 WO disclosed
WO-2007003581-A1 PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS NOVO NORDISK A/S (DK) 2007-01-11 WO disclosed
WO-2007003604-A2 HISTS1MINE H3 RECEPTOR ANTAGONISTS NOVO NORDISK A/S (DK) 2007-01-11 WO disclosed
WO-2006087309-A1 3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID 5-AMINOPYRIDIN-2-YL ESTERS NOVO NORDISK A/S (DK) 2006-08-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240051972-A1 Compounds Useful in HIV Therapy CD4, CCR5, ABCB1 EPAS1 3364/4885MBTD1 4279/4885L3MBTL3 2557/4885
US-20240182473-A1 COMPOUNDS USEFUL IN HIV THERAPY CD4, CCR5, G6PD EPAS1 3064/4885MBTD1 4373/4885L3MBTL3 3109/4885
US-20240140970-A1 A DEUTERATED COMPOUND, AND PREPARATION METHOD AND USE THEREOF DMPK, DEK, DOHH EPAS1 2238/4885MBTD1 662/4885L3MBTL3 3120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.