Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912707 | 0.84 | HTR1A (0.38) | CYP3A4SMN1; SMN2 | |
| SCHEMBL7048859 | 0.84 | RORC (0.37) | CYP3A4SMN1; SMN2SRD5A2GLRA1 | |
| SCHEMBL7899724 | 0.81 | ALDH1A1 (0.36) | CYP3A4SMN1; SMN2 | |
| SCHEMBL7899686 | 0.81 | CYP3A4 (0.32) | CYP3A4SMN1; SMN2 | |
| SCHEMBL7899687 | 0.78 | NR1H2 (0.35) | CYP3A4SMN1; SMN2PPARG | |
| SCHEMBL346407 | 0.73 | SMN1; SMN2 (0.57) | CYP3A4SMN1; SMN2RARB | |
| SCHEMBL7908953 | 0.72 | VDR (0.47) | — | |
| SCHEMBL8681820 | 0.70 | THRA (0.39) | RARBSRD5A2GLRA1 | |
| SCHEMBL5873464 | 0.70 | GABRA1 (0.50) | CYP3A4 | |
| SCHEMBL7912756 | 0.69 | ESR1 (0.38) | CYP3A4SMN1; SMN2RARARARBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187493-B1 | CHARGE GENERATING MATERIAL AND ELECTRON TRANSFER MATERIAL UNIFORMLY DISPERSED WITHIN COMPATIBLE POLYESTER BINDER; PHOTOSENSITIVITY, WEAR RESISTANCE, ADHESION TO ELECTROCONDUCTIVE SUBSTRATE | KYOCERA MITA CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0738934-A2 | Electrophotosensitive material | MITA INDUSTRIAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |