Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681277 | 0.90 | ALDH1A1 (0.41) | KDM4EHPGDHSD17B10SMN1; SMN2HTT | |
| SCHEMBL10012889 | 0.89 | KDM4E (0.43) | KDM4EHPGDHSD17B10TP53APAF1 | |
| SCHEMBL7907604 | 0.88 | HPGD (0.44) | KDM4EHPGDHSD17B10TP53APAF1 | |
| SCHEMBL12735455 | 0.88 | ALDH1A1 (0.43) | KDM4EHPGDHSD17B10TP53APAF1 | |
| SCHEMBL13484442 | 0.87 | ALDH1A1 (0.42) | KDM4EHPGDHSD17B10TP53APAF1 | |
| SCHEMBL7901976 | 0.87 | CDC7 (0.38) | KDM4EHSD17B10SMN1; SMN2HTTKMT2A | |
| SCHEMBL4547065 | 0.86 | ALDH1A1 (0.45) | KDM4EHPGDHSD17B10TP53APAF1 | |
| SCHEMBL29886558 | 0.85 | ADORA3 (0.40) | KDM4EHPGDHSD17B10TP53APAF1 | |
| SCHEMBL12735454 | 0.84 | MTOR (0.40) | KDM4EHPGDHSD17B10TP53APAF1 | |
| SCHEMBL10196895 | 0.84 | MTOR (0.40) | KDM4EHPGDHSD17B10TP53APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204266-B1 | TREATING INFLAMMATION OR CANCER SENSITIVITY BY ADMINISTERING A PYRAZINE DERIVATIVE IN A COSMETIC OR FOOD CARRIER TO EXHIBIT AN ANTIOXIDANT EFFECT | UNIVERSITE CATHOLIQUE DE LOUVAIN HALLES UNIVERSITAIRES (BE) | 2001-03-20 | — | — | US | claimed |
| US-9399657-B2 | Chemiluminescent methods and reagents for analyte detection | WANG TIANXIN (US) | 2016-07-26 | — | — | US | disclosed |
| US-20110097753-A1 | Chemiluminescent methods and reagents for analyte detection | WANG TIANXIN | 2011-04-28 | — | — | US | disclosed |
| US-6204266-B1 | TREATING INFLAMMATION OR CANCER SENSITIVITY BY ADMINISTERING A PYRAZINE DERIVATIVE IN A COSMETIC OR FOOD CARRIER TO EXHIBIT AN ANTIOXIDANT EFFECT | UNIVERSITE CATHOLIQUE DE LOUVAIN HALLES UNIVERSITAIRES (BE) | 2001-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110097753-A1 | Chemiluminescent methods and reagents for analyte detection | UCHL1, LCT, SPR | KDM4E 2396/4885HPGD 827/4885HSD17B10 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.