Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12735455 | 0.99 | ALDH1A1 (0.43) | KDM4EHPGDHSD17B10ADORA3TP53 | |
| SCHEMBL4547065 | 0.97 | ALDH1A1 (0.45) | KDM4EHPGDHSD17B10ADORA3TP53 | |
| SCHEMBL13484442 | 0.95 | ALDH1A1 (0.42) | KDM4EHPGDHSD17B10ADORA3TP53 | |
| SCHEMBL29886558 | 0.95 | ADORA3 (0.40) | KDM4EHPGDHSD17B10ADORA3TP53 | |
| SCHEMBL10196895 | 0.94 | MTOR (0.40) | KDM4EHPGDHSD17B10ADORA3TP53 | |
| SCHEMBL12735454 | 0.94 | MTOR (0.40) | KDM4EHPGDHSD17B10ADORA3TP53 | |
| SCHEMBL19810194 | 0.92 | ALDH1A1 (0.39) | KDM4EHPGDHSD17B10ADORA3TP53 | |
| SCHEMBL19206678 | 0.90 | LTB4R (0.47) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7907590 | 0.89 | KDM4E (0.48) | KDM4EHPGDHSD17B10ADORA3TP53 | |
| SCHEMBL492636 | 0.89 | LTB4R (0.41) | KDM4EHPGDHSD17B10ADORA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160362388-A1 | CHEMILUMINESCENT METHODS AND REAGENTS FOR ANALYTE DETECTION | WANG TIANXIN (US) | 2016-12-15 | — | — | US | disclosed |
| US-9487520-B2 | Coelenterazine derivatives and methods of using same | PROMEGA CORPORATION (US) | 2016-11-08 | — | — | US | disclosed |
| US-9399657-B2 | Chemiluminescent methods and reagents for analyte detection | WANG TIANXIN (US) | 2016-07-26 | — | — | US | disclosed |
| EP-2454261-B1 | IMIDAZO[1,2-ALPHA]PYRAZIN-3(7H)-ONE DERIVATIVES BEARING A NEW ELECTRON-RICH STRUCTURE | UNIV SIENA (IT) | 2014-11-19 | — | — | EP | disclosed |
| US-8546147-B2 | Imidazo[1,2-α]pyrazin-3(7H)-one derivatives bearing a new electron-rich structure | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2013-10-01 | — | — | US | disclosed |
| US-20120171703-A1 | IMIDAZO[1,2-ALPHA]PYRAZIN-3(7H)-ONE DERIVATIVES BEARING A NEW ELECTRON-RICH STRUCTURE | UNIVERSITÁ DEGLI STUDI DI SIENA (IT) | 2012-07-05 | — | — | US | disclosed |
| US-20110097753-A1 | Chemiluminescent methods and reagents for analyte detection | WANG TIANXIN | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362388-A1 | CHEMILUMINESCENT METHODS AND REAGENTS FOR ANALYTE DETECTION | UCHL1, LCT, SPR | KDM4E 2396/4885HPGD 827/4885HSD17B10 467/4885 |
| US-20120171703-A1 | IMIDAZO[1,2-ALPHA]PYRAZIN-3(7H)-ONE DERIVATIVES BEARING A NEW ELECTRON-RICH STRUCTURE | GLB1, NDUFV1, IK | KDM4E 4676/4885HPGD 377/4885HSD17B10 1662/4885 |
| US-20110097753-A1 | Chemiluminescent methods and reagents for analyte detection | UCHL1, LCT, SPR | KDM4E 2396/4885HPGD 827/4885HSD17B10 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.