Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 4/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906572 | 0.80 | PDE4A (0.51) | PDE4AHPGDCASP1MEN1KMT2A | |
| SCHEMBL10392397 | 0.77 | CYP1A2 (0.54) | ALDH1A1GAAPDE4DHPGDCYP1A2 | |
| SCHEMBL4827006 | 0.74 | ALDH1A1 (0.53) | ALDH1A1GAAPDE4APDE4BPDE4C | |
| SCHEMBL7904298 | 0.73 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL7991282 | 0.72 | LMNA (0.54) | ALDH1A1GAAPDE4APDE4BPDE4C | |
| SCHEMBL7908376 | 0.72 | PDE4A (0.44) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7905359 | 0.72 | PDE4A (0.65) | PDE4A | |
| SCHEMBL17602246 | 0.71 | MAPT (0.41) | GAARXFP1LTC4STUBB4ATUBB | |
| SCHEMBL27830996 | 0.69 | LTC4S (0.41) | LTC4SRXRAMAPT | |
| SCHEMBL7994597 | 0.68 | LMNA (0.43) | PDE4APDE4BPDE4CPDE4DVNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200993-B1 | ASTHMA; ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-03-13 | — | — | US | disclosed |