⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706308 | 0.82 | RNASE1 (0.39) | — | |
| SCHEMBL7908351 | 0.79 | TK2 (0.35) | — | |
| SCHEMBL1705943 | 0.78 | TK1 (0.35) | — | |
| SCHEMBL6756344 | 0.78 | RNASE1 (0.37) | — | |
| SCHEMBL1705788 | 0.76 | ABCG2 (0.34) | — | |
| SCHEMBL29414069 | 0.76 | LMNA (0.37) | — | |
| SCHEMBL3612842 | 0.76 | PYGM (0.38) | — | |
| SCHEMBL5954363 | 0.74 | TK2 (0.33) | — | |
| SCHEMBL5031652 | 0.73 | — | — | |
| SCHEMBL29414053 | 0.73 | RNASE1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422090-B1 | DERIVATIVES OF NUCLEOSIDES WHICH MAY BE USED FOR THE SYNTHESIS OF MARKED OLIGONUCLEOTIDES, AND OLIGONUCLEOTIDES OBTAINED FROM THESE DERIVATIVES AND THEIR SYNTHESIS | CIS BIO INTERNATIONAL (FR) | 1993-06-02 | — | — | EP | disclosed |
| EP-0422090-A1 | DERIVATIVES OF NUCLEOSIDES WHICH MAY BE USED FOR THE SYNTHESIS OF MARKED OLIGONUCLEOTIDES, AND OLIGONUCLEOTIDES OBTAINED FROM THESE DERIVATIVES AND THEIR SYNTHESIS. | CIS BIO INT (FR) | 1991-04-17 | — | — | EP | disclosed |
| WO-1989012642-A1 | DERIVATIVES OF NUCLEOSIDES WHICH MAY BE USED FOR THE SYNTHESIS OF MARKED OLIGONUCLEOTIDES, AND OLIGONUCLEOTIDES OBTAINED FROM THESE DERIVATIVES AND THEIR SYNTHESIS | CIS BIO INTERNATIONAL (FR) | 1989-12-28 | — | — | WO | disclosed |