Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599359 | 0.88 | CDC25B (0.50) | KEAP1NFE2L2CRHBPCRHR2KDM4E | |
| SCHEMBL30881836 | 0.77 | KEAP1 (0.44) | BTKKEAP1BCAT2ALOX5APFEN1 | |
| SCHEMBL30646218 | 0.75 | BCAT2 (0.63) | BTKKEAP1NFE2L2KDM4EALDH1A1 | |
| SCHEMBL30841448 | 0.75 | BCAT2 (0.69) | KEAP1NFE2L2CRHBPCRHR2KDM4E | |
| SCHEMBL27651120 | 0.74 | MMP2 (0.45) | BTKKEAP1NFE2L2KDM4EALDH1A1 | |
| SCHEMBL6061358 | 0.74 | ALDH1A1 (0.56) | KEAP1KDM4EALDH1A1GAAPARP1 | |
| SCHEMBL5748491 | 0.74 | ATM (0.62) | BTKKDM4EALDH1A1GAABCAT2 | |
| SCHEMBL30623038 | 0.74 | MMP2 (0.45) | BTKKEAP1NFE2L2KDM4EALDH1A1 | |
| SCHEMBL634722 | 0.73 | ATM (0.55) | KEAP1NFE2L2KDM4EALDH1A1GAA | |
| SCHEMBL29733181 | 0.73 | PARP1 (0.58) | KEAP1NFE2L2ALDH1A1GAABCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |