SCHEMBL7909371

SCHEMBL7909371

C[Si](C)(C)OC(=O)c1cc(O[Si](C)(C)C)cc(O[Si](C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.33
MAPT P10636 1/20 0.33
ALDH1A1 P00352 1/20 0.33
F11 P03951 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
NFKB1 P19838 1/20 0.31
XDH P47989 1/20 0.31
GFER P55789 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
FUT7 Q11130 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14556880 0.82 KDM4E (0.33) KDM4EMAPTALDH1A1F11CA12
SCHEMBL5343627 0.79 PLA2G2A (0.46) KDM4EMAPTALDH1A1CA12CA1
SCHEMBL3519634 0.78 KDM4E (0.31) KDM4ELMNAGAA
SCHEMBL14556878 0.77 MEN1 (0.39) KDM4EMAPTALDH1A1CA12CA9
SCHEMBL9517612 0.75 ALDH1A1 (0.39) ALDH1A1
SCHEMBL7558007 0.74 CA12 (0.39) KDM4EMAPTCA12CA1CA9
SCHEMBL7902130 0.73 GLRA1 (0.31)
SCHEMBL12213023 0.73 PTPN11 (0.45) KDM4ECA12CA1CA2CA7
SCHEMBL8460883 0.73 CA1 (0.44) KDM4EMAPTALDH1A1CA12CA1
SCHEMBL11091233 0.71 LOXL2 (0.42) ALDH1A1LMNAPOLBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6300424-B1 Hyperbranched polyesters and polyamides CORNELL RESEARCH FOUNDATION, INC. 2001-10-09 US disclosed
EP-0558556-B1 HYPERBRANCHED POLYESTERS CORNELL RES FOUNDATION INC (US) 1997-04-23 EP disclosed
US-5514764-A Hyperbranched polyesters and polyamides CORNELL RESEARCH FOUNDATION, INC. (US) 1996-05-07 US disclosed
EP-0558556-A1 HYPERBRANCHED POLYESTERS AND POLYAMIDES. CORNELL RES FOUNDATION INC (US) 1993-09-08 EP disclosed
WO-1992008749-A1 HYPERBRANCHED POLYESTERS AND POLYAMIDES CORNELL RESEARCH FOUNDATION, INC. (US) 1992-05-29 WO disclosed