Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908101 | 0.91 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7906977 | 0.91 | CNR2 (0.41) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7910522 | 0.86 | KCNE1 (0.43) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL7910178 | 0.80 | KCNE1 (0.42) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL6601917 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7900359 | 0.79 | KCNE1 (0.41) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL7913688 | 0.76 | CTSD (0.36) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL7910164 | 0.74 | SIRT2 (0.39) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL6559382 | 0.74 | MAPT (0.45) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL7464900 | 0.73 | KCNE1 (0.52) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |