Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290864 | 0.77 | ALDH1A1 (0.37) | KMT2AALDH1A1NPC1RAB9A | |
| Bicarbonate SCHEMBL7360481 | 0.71 | NPC1 (0.47) | KMT2ALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL8147442 | 0.70 | ALDH1A1 (0.39) | KMT2ALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL5784672 | 0.69 | PDE4A (0.40) | KMT2ALMNANPC1RAB9A | |
| SCHEMBL7846691 | 0.69 | NPC1 (0.46) | KMT2ALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL2378171 | 0.69 | LMNA (0.60) | KMT2ALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL5786283 | 0.65 | NPC1 (0.44) | KMT2ALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL15392653 | 0.65 | OPRD1 (0.44) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7552940 | 0.64 | LTB4R (0.47) | ALOX15MAPTMTNR1AMTNR1B | |
| SCHEMBL7557806 | 0.64 | LTB4R (0.47) | ALOX15MAPTMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211203-B1 | RESPIRATORY SYSTEM DISORDERS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-04-03 | — | — | US | disclosed |