Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594505 | 0.92 | SMN1; SMN2 (0.41) | FBP1TSHRSMN1; SMN2POLBGALR2 | |
| SCHEMBL7596229 | 0.80 | KMT2A (0.42) | FBP1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7916876 | 0.80 | POLB (0.48) | SMN1; SMN2POLBMITFALDH1A1KMT2A | |
| SCHEMBL7596218 | 0.78 | LMNA (0.43) | FBP1TSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL7910018 | 0.78 | L3MBTL1 (0.49) | SMN1; SMN2ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL7594895 | 0.77 | RAB9A (0.49) | ALDH1A1LMNAKMT2AMEN1HTT | |
| SCHEMBL7593575 | 0.76 | KDM4C (0.42) | FBP1TSHRSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL7596958 | 0.76 | KDM4E (0.46) | POLBALDH1A1LMNAKMT2AAKR1C3 | |
| SCHEMBL7596188 | 0.76 | ALDH1A1 (0.42) | ALDH1A1LMNAABCB1KMT2AMEN1 | |
| SCHEMBL7598810 | 0.76 | RAB9A (0.56) | TSHRALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211177-B1 | SIDE EFFECT REDUCTION | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | disclosed |