SCHEMBL7915228

SCHEMBL7915228

O=C1C(=O)C(CC2C(=O)C(=O)c3ccccc3C2=O)C(=O)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
CDC25B P30305 2/20 0.48
MAPT P10636 5/20 0.46
POLB P06746 3/20 0.46
S100A4 P26447 3/20 0.46
LMNA P02545 3/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPK1 P28482 2/20 0.46
APAF1 O14727 2/20 0.46
TDP2 O95551 2/20 0.46
RAB9A P51151 2/20 0.46
BLM P54132 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
THRB P10828 2/20 0.46
MAOA P21397 2/20 0.46
CES2 O00748 1/20 0.46
TERT O14746 1/20 0.46
NPC1 O15118 1/20 0.46
PLIN1 O60240 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22272423 0.77 PARK7 (0.45) ALDH1A1CASP3
SCHEMBL23043833 0.76 CDC25B (0.53) KMT2ACDC25BMAPTRAB9ANPC1
SCHEMBL23044111 0.74 LMNA (0.50) MEN1KMT2ACDC25BMAPTPOLB
SCHEMBL12458500 0.72 MEN1 (0.45) MEN1KMT2AMAPTPOLBS100A4
SCHEMBL30845852 0.72 MEN1 (0.45) MEN1KMT2AMAPTPOLBS100A4
SCHEMBL18053325 0.72 MEN1 (0.45) MEN1KMT2AMAPTPOLBS100A4
SCHEMBL86112 0.71 KMT2A (0.48) MEN1KMT2ACDC25BMAPTPOLB
SCHEMBL8365427 0.71 ALDH1A1 (0.58) MEN1KMT2ACDC25BMAPTPOLB
SCHEMBL10287951 0.71 MEN1 (0.48) MEN1KMT2ACDC25BMAPTPOLB
SCHEMBL2126258 0.70 S100A4 (0.58) MEN1KMT2ACDC25BMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed