Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | BCHE | P06276 | 7/20 | 0.64 |
| ▸ | ACHE | P22303 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915315 | 1.00 | LMNA (0.64) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL7915244 | 1.00 | LMNA (0.64) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL7915247 | 1.00 | LMNA (0.64) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL7921547 | 0.99 | LMNA (0.66) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL7921543 | 0.99 | LMNA (0.66) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL4018801 | 0.94 | LMNA (0.71) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL4018802 | 0.94 | LMNA (0.71) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL4023889 | 0.88 | ALDH1A1 (0.72) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL4023891 | 0.88 | ALDH1A1 (0.72) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL13833758 | 0.88 | AKR1B10 (0.71) | LMNAALDH1A1AKR1B10AKR1B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200831-B1 | HEAT-CURING A COATING OF A POLYAMIC ACID BASED ON A TETRACARBOXYLIC ACID AND A DIAMINE CONTAINNG AN ACTIVE OXYGEN OR NITROGEN FUNCTIONAL GROUP; SEALING THE EXTERNAL TERMINALS WITH A RESIN, E.G. AN EPOXIDE | HITACHI, LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| US-6087006-A | SEMICONDUCTOR DEVICE HAVING SURFACE-PROTECTING FILM COMPRISING POLYIMIDE OBTAINED BY HEAT-CURING PRECURSOR HAVING POLAR SUBSTITUENTS AS THE SIDE CHAINS | HITACHI, LTD. (JP) | 2000-07-11 | — | — | US | disclosed |