Sugi Predict

Sugi Predict / Compounds / SCHEMBL7915387

SCHEMBL7915387

SCHEMBL7915387

Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1C(=O)COc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 6/20 0.60
▸ ADORA2B P29275 5/20 0.60
▸ ADORA3 P0DMS8 5/20 0.55
▸ ADORA1 P30542 3/20 0.54
▸ CYP1A2 P05177 2/20 0.53
▸ THPO P40225 1/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ CYP2D6 P10635 1/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ BLM P54132 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3967723 0.88 ADORA3 (0.59) ADORA2AADORA2BADORA3ADORA1
SCHEMBL5347463 0.85 CYP1A2 (0.66) ADORA2AADORA2BADORA3ADORA1CYP1A2
SCHEMBL784431 0.84 ADORA2A (0.54) ADORA2AADORA2BADORA3ADORA1CYP1A2
SCHEMBL217116 0.83 CYP2C19 (0.60) ADORA2AADORA2BADORA3ADORA1CYP2C19
SCHEMBL5358560 0.83 ADORA2A (0.53) ADORA2AADORA2BADORA3CYP2C19
SCHEMBL27690308 0.81 ADORA2A (0.60) ADORA2AADORA2BADORA3ADORA1
SCHEMBL2208478 0.81 ADORA2A (0.60) ADORA2AADORA2BADORA3ADORA1
SCHEMBL1611240 0.80 ADORA2A (0.57) ADORA2AADORA2BADORA3ADORA1CYP2C19
SCHEMBL4813930 0.80 ADORA2A (0.57) ADORA2AADORA2BADORA3ADORA1CYP2C19
SCHEMBL5347799 0.80 ADORA2A (0.60) ADORA2AADORA2BADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400168-A2 ANTISENSE NUCLEIC ACIDS Nippon Shinyaku Co., Ltd. (JP) 2024-07-17 — — EP disclosed
US-20230151050-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2023-05-18 — — US disclosed
US-20210340171-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2021-11-04 — — US disclosed
US-20210284680-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2021-09-16 — — US disclosed
US-20210198306-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2021-07-01 — — US disclosed
US-20210179659-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2021-06-17 — — US disclosed
US-11028122-B1 Antisense nucleic acids NIPPON SHINYAKU CO., LTD. (JP) 2021-06-08 — — US disclosed
US-10870676-B2 Antisense nucleic acids NIPPON SHINYAKU CO., LTD. (JP) 2020-12-22 — — US disclosed
US-10683322-B2 Antisense nucleic acids NIPPON SHINYAKU CO., LTD. (JP) 2020-06-16 — — US disclosed
US-10662217-B2 Antisense nucleic acids NIPPON SHINYAKU CO., LTD. (JP) 2020-05-26 — — US disclosed
EP-2612917-B1 ANTISENSE NUCLEIC ACID NIPPON SHINYAKU CO LTD (JP) 2016-02-24 — — EP disclosed
US-9079934-B2 Antisense nucleic acids NIPPON SHINYAKU CO., LTD. (JP) 2015-07-14 — — US disclosed
US-20150166995-A1 ANTISENSE NUCLEIC ACIDS NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY (JP) 2015-06-18 — — US disclosed
US-8969551-B2 Morpholino nucleic acid derivatives NIPPON SHINYAKU CO., LTD. (JP) 2015-03-03 — — US disclosed
US-20130211062-A1 ANTISENSE NUCLEIC ACIDS NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY (JP) 2013-08-15 — — US disclosed
EP-2623507-A1 MORPHOLINO NUCLEIC ACID DERIVATIVE Nippon Shinyaku Co., Ltd. (JP) 2013-08-07 — — EP disclosed
US-20130197220-A1 Morpholino Nucleic Acid Derivatives NIPPON SHINYAKU CO., LTD. (JP) 2013-08-01 — — US disclosed
EP-2612917-A1 ANTISENSE NUCLEIC ACID Nippon Shinyaku Co., Ltd. (JP) 2013-07-10 — — EP disclosed
EP-1159064-A1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2001-12-05 — — EP disclosed
WO-2000053309-A1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2000-09-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11028122-B1 Antisense nucleic acids UTRN, RBM17, UPF1 ADORA2A 1931/4885ADORA2B 1556/4885ADORA3 1133/4885
US-10662217-B2 Antisense nucleic acids UTRN, RBM17, UPF1 ADORA2A 1931/4885ADORA2B 1556/4885ADORA3 1133/4885
US-20210198306-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 ADORA2A 1931/4885ADORA2B 1556/4885ADORA3 1133/4885
US-20130197220-A1 Morpholino Nucleic Acid Derivatives MORF4L1, METTL16, METTL3 ADORA2A 3560/4885ADORA2B 3501/4885ADORA3 2355/4885
US-20210284680-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 ADORA2A 1931/4885ADORA2B 1556/4885ADORA3 1133/4885
US-20210340171-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 ADORA2A 1931/4885ADORA2B 1556/4885ADORA3 1133/4885
US-20230151050-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 ADORA2A 1931/4885ADORA2B 1556/4885ADORA3 1133/4885
US-20130211062-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 ADORA2A 1807/4885ADORA2B 1267/4885ADORA3 825/4885
US-20210179659-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 ADORA2A 1931/4885ADORA2B 1556/4885ADORA3 1133/4885
US-10870676-B2 Antisense nucleic acids UTRN, RBM17, UPF1 ADORA2A 1931/4885ADORA2B 1556/4885ADORA3 1133/4885
US-10683322-B2 Antisense nucleic acids UTRN, RBM17, UPF1 ADORA2A 1931/4885ADORA2B 1556/4885ADORA3 1133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.