Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564617 | 0.79 | LMNA (0.39) | CES2CES1 | |
| SCHEMBL6475627 | 0.76 | CES2 (0.44) | CES2CES1ESR1CYP19A1 | |
| SCHEMBL13236533 | 0.75 | ALDH1A1 (0.56) | PTGS2CES2CES1CYP19A1 | |
| SCHEMBL6344467 | 0.75 | ALDH1A1 (0.56) | PTGS2CES2CES1CYP19A1 | |
| SCHEMBL6344463 | 0.75 | ALDH1A1 (0.56) | PTGS2CES2CES1CYP19A1 | |
| SCHEMBL22750629 | 0.75 | CES2 (0.53) | PTGS2CES2CES1CYP19A1 | |
| SCHEMBL13236532 | 0.73 | ALDH1A1 (0.49) | PTGS2CNR2ESR1PPARGPPARA | |
| SCHEMBL27885832 | 0.73 | CES2 (0.48) | PTGS2CES2CES1ESR1 | |
| SCHEMBL27552729 | 0.73 | CES2 (0.50) | PTGS2CES2CES1 | |
| SCHEMBL27509228 | 0.73 | PTGS2 (0.47) | PTGS2CES2CES1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221115-B1 | WHITE, DYED, DIPPED, UNSCENTED AND/OR SCENTED CANDLE WAX STABILIZED BY A ULTRAVILET RADIATION ABSORBER AND HINDERED AMINE STABILIZING AGENT | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-04-24 | — | — | US | disclosed |