SCHEMBL7916766

SCHEMBL7916766

CO[Si](OC)(OC)C(C)Cc1ccccc1OC#N

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
KCNH2 Q12809 1/20 0.31
IDO1 P14902 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
TSHR P16473 1/20 0.30
GCK P35557 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7906949 0.85 ADRA2A (0.32) KMT2AKDM4EGAASLC6A2SLC6A4
SCHEMBL8601635 0.83 KMT2A (0.32) KMT2AKDM4EGAASLC6A2SLC6A4
SCHEMBL19824384 0.80 KMT2A (0.36) KMT2AKDM4EGAASLC6A2SLC6A4
SCHEMBL7906970 0.73 ALDH1A1 (0.33)
SCHEMBL7916891 0.73 TSHR (0.32) KDM4ETSHR
SCHEMBL7917107 0.72 ALOX15 (0.43) KMT2AKDM4E
SCHEMBL9167140 0.72 SLC6A2 (0.43) KMT2ASLC6A2SLC6A4IDO1TAAR1
SCHEMBL7917112 0.72 SLC6A4 (0.39) SLC6A4
SCHEMBL7906930 0.72 TAAR1 (0.42) KDM4EGAAKCNH2IDO1TAAR1
SCHEMBL31084413 0.71 L3MBTL1 (0.48) KDM4ESLC6A2SLC6A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6217943-B1 ADHESION AND REINFORCEMENT WITH SILANE CYANATE COUPLERS 3M INNOVATIVE PROPERTIES COMPANY 2001-04-17 US disclosed
US-5912377-A CONTAINING AT LEAST ONE CYANATE ESTER GROUP AND HYDROLYZABLE SILYL GROUP; REINFORCED COMPOSITES, ADESIVES, COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-15 US disclosed
EP-0830410-B1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING & MFG (US) 1999-04-07 EP disclosed
EP-0830410-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-25 EP disclosed
WO-1996039457-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-12 WO disclosed