SCHEMBL8601635

SCHEMBL8601635

CC(Cc1ccccc1OC#N)[Si](Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A2 P23975 1/20 0.32
KCNH2 Q12809 1/20 0.32
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7916766 0.83 KMT2A (0.34) KMT2AKDM4EGAASLC6A4SLC6A2
SCHEMBL19824384 0.82 KMT2A (0.36) KMT2AKDM4EGAASLC6A4SLC6A2
SCHEMBL7906949 0.81 ADRA2A (0.32) KMT2AKDM4EGAASLC6A4SLC6A2
SCHEMBL7917098 0.79 TAAR1 (0.30)
SCHEMBL7920316 0.72 ALDH1A1 (0.31) KDM4ESLC6A4
SCHEMBL7917068 0.72 TAAR1 (0.33)
SCHEMBL31084413 0.72 L3MBTL1 (0.48) KDM4ESLC6A4SLC6A2
SCHEMBL6748000 0.72 L3MBTL1 (0.48) KDM4ESLC6A4SLC6A2
SCHEMBL156947 0.72 CYP1A2 (0.37) SLC6A4
SCHEMBL27668716 0.72 HTR1A (0.42) SLC6A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830410-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-25 EP disclosed
WO-1996039457-A1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-12 WO disclosed