Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593521 | 0.84 | ALDH1A1 (0.47) | HCAR3CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL27879474 | 0.81 | HCAR3 (0.55) | HCAR3CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL7596215 | 0.80 | ALDH1A1 (0.51) | HCAR3ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7593566 | 0.79 | KMT2A (0.46) | HCAR3ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7600452 | 0.75 | LTB4R (0.48) | LMNAMAPTGAARAB9A | |
| SCHEMBL7591179 | 0.74 | LTB4R (0.45) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL7593459 | 0.74 | ALDH1A1 (0.47) | HCAR3CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL7594793 | 0.74 | LMNA (0.51) | HCAR3CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL27879453 | 0.74 | RXRA (0.44) | HCAR3CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL27845365 | 0.73 | HCAR3 (0.58) | HCAR3ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211177-B1 | SIDE EFFECT REDUCTION | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | disclosed |