Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932556 | 0.84 | KMO (0.40) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL28172626 | 0.84 | KCNQ3 (0.37) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL7929303 | 0.84 | KDR (0.41) | F2CTSSCTSKRAB9ATYK2 | |
| SCHEMBL7918733 | 0.81 | KIF11 (0.37) | LMNAKIF11CES2SCN9AVNN1 | |
| SCHEMBL5800279 | 0.81 | CES2 (0.39) | F2PDK2CES2PBRM1NPC1 | |
| SCHEMBL7920531 | 0.80 | HTR3E (0.41) | F2RAB9ATYK2HTTSCN9A | |
| SCHEMBL7920540 | 0.78 | NOTUM (0.45) | PDK2KIF11HTTKDM4EMAPT | |
| SCHEMBL8676513 | 0.77 | PBRM1 (0.43) | PBRM1ALDH1A1CASP1 | |
| SCHEMBL8157649 | 0.74 | ALDH1A1 (0.47) | PDK2LMNAXBP1RAB9AKDM4E | |
| SCHEMBL2842495 | 0.74 | POLB (0.42) | RAB9ACYP1A2CYP2C19PBRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847977-B1 | 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | NIPPON SODA CO (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6054605-A | CHEMICAL INTERMEDIATE FOR DRUGS, PESTICIDES | NIPPON SODA CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| US-6054624-A | USEFUL AS THE STARTING MATERIALS FOR PRODUCING PESTICIDES, DRUGS AND THE LIKE | NIPPON SODA CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0847977-A1 | 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | NIPPON SODA CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |