Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | PLAT | P00750 | 2/20 | 0.33 |
| ▸ | KLK1 | P06870 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916601 | 0.80 | TNF (0.43) | F2PLGPLAUPLATKLK1 | |
| SCHEMBL16502725 | 0.78 | SLC22A12 (0.44) | CHEK1CHEK2IDO1ARPLAU | |
| SCHEMBL7920052 | 0.74 | CYP19A1 (0.45) | IMPDH2PLAU | |
| SCHEMBL7919941 | 0.73 | PLAU (0.41) | F2PLGPLAUPLATKLK1 | |
| SCHEMBL7915669 | 0.71 | HTR5A (0.41) | F2PLGPLAUPLATKLK1 | |
| SCHEMBL7451090 | 0.70 | IDO1 (0.47) | IDO1ARIMPDH2PLAURBDKRB2 | |
| SCHEMBL7918769 | 0.69 | CNR2 (0.39) | F2PLGPLAUPLATKLK1 | |
| SCHEMBL7916046 | 0.69 | HTR5A (0.39) | F2PLGPLAUPLATKLK1 | |
| SCHEMBL26259995 | 0.68 | TBXAS1 (0.44) | IDO1ARIMPDH2PLAURCD38 | |
| SCHEMBL7918264 | 0.68 | SLC9A1 (0.49) | ARPLAUSLC9A1HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |