Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972104 | 0.80 | HSD11B1 (0.46) | ALDH1A1LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL5921807 | 0.75 | LMNA (0.50) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL1194484 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL216367 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL545684 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| Phosphine SCHEMBL2238711 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL11020611 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1MAPTALOX15 | |
| SCHEMBL216974 | 0.71 | HSD11B1 (0.49) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL20034068 | 0.70 | GABRA1 (0.50) | ALDH1A1TSHRTDP1IDO1HPGD | |
| SCHEMBL1030000 | 0.70 | LMNA (0.41) | ALDH1A1TSHRTDP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791607-B1 | Substituted metallocene catalyst for the (co)polymerization of olefins | ENICHEM SPA (IT) | 2001-05-02 | — | — | EP | disclosed |