Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 6/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
| ▸ | GRK3 | P35626 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924925 | 0.88 | MMP1 (0.48) | MMP1MMP13MMP9SMN1; SMN2 | |
| SCHEMBL7360052 | 0.68 | SMN1; SMN2 (0.47) | MMP1MMP13MMP9SMN1; SMN2 | |
| SCHEMBL2565817 | 0.65 | HDAC8 (0.57) | SMN1; SMN2AKR1C3 | |
| SCHEMBL7924934 | 0.65 | MMP1 (0.46) | MMP1MMP9 | |
| SCHEMBL30622718 | 0.61 | SMN1; SMN2 (0.50) | SMN1; SMN2 | |
| SCHEMBL2533132 | 0.61 | SMN1; SMN2 (0.50) | SMN1; SMN2 | |
| SCHEMBL18184671 | 0.61 | PSIP1 (0.59) | SMN1; SMN2PGR | |
| SCHEMBL2560113 | 0.60 | LMNA (0.48) | SMN1; SMN2 | |
| SCHEMBL7928511 | 0.60 | MMP1 (0.51) | MMP1MMP13MMP9SMN1; SMN2 | |
| SCHEMBL7557556 | 0.60 | MMP1 (0.57) | MMP1MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | disclosed |