SCHEMBL7925112

SCHEMBL7925112

CC(=O)OCC(C)CCCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 1/20 0.45
LMNA P02545 2/20 0.45
PKM P14618 1/20 0.44
CHRNB2 P17787 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
CHRNA4 P43681 1/20 0.44
HDAC3 O15379 1/20 0.43
MAPK1 P28482 1/20 0.43
ADRA1A P35348 1/20 0.43
HDAC4 P56524 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HDAC1 Q13547 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6682726 0.81 NAAA (0.50) ALDH1A1CYP2D6CYP2C9CYP2C19KMT2A
SCHEMBL10886546 0.80 ALDH1A1 (0.56) ALDH1A1CYP2C9CYP2C19KMT2ALMNA
SCHEMBL16137501 0.80 ALDH1A1 (0.56) ALDH1A1CYP2C9CYP2C19KMT2ALMNA
SCHEMBL15247513 0.80 ALDH1A1 (0.56) ALDH1A1CYP2C9CYP2C19KMT2ALMNA
SCHEMBL6505023 0.79 ALDH1A1 (0.55) ALDH1A1KMT2ASMN1; SMN2HPGDTSHR
SCHEMBL19090603 0.77 SIGMAR1 (0.50) KMT2A
SCHEMBL8440945 0.77 ADRB2 (0.55) LMNAPKMHDAC3MAPK1ADRA1A
SCHEMBL19024844 0.77 ADRB2 (0.55) LMNAPKMHDAC3MAPK1ADRA1A
SCHEMBL1051 0.76 LMNA (0.68) ALDH1A1CYP2D6LMNAHDAC3MAPK1
SCHEMBL6559718 0.76 ALDH1A1 (0.51) ALDH1A1KMT2ACHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310033-B1 2,4-DIMETHYL-5-PHENYLPENTANAL; PERFUMES BUSH BOAKE ALLEN INC. 2001-10-30 US disclosed