Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925096 | 0.93 | KMT2A (0.52) | MMP8CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL7925086 | 0.81 | KMT2A (0.40) | POLBCA12CA9CYP2C9CYP2C19 | |
| SCHEMBL9192833 | 0.79 | POLB (0.61) | ADAM17POLBCA12CA2CA9 | |
| SCHEMBL10635162 | 0.79 | POLB (0.61) | ADAM17POLBCA12CA2CA9 | |
| SCHEMBL7924570 | 0.79 | METAP2 (0.60) | POLBMETAP2CA12CA2CA9 | |
| SCHEMBL6232756 | 0.73 | KMT2A (0.59) | POLBCA12CA2CA9MMP8 | |
| SCHEMBL10492080 | 0.72 | POLB (0.61) | POLBCA12CA2CA9MMP8 | |
| SCHEMBL9188615 | 0.72 | POLB (0.54) | POLBMETAP2CA12CA2CA9 | |
| SCHEMBL7916657 | 0.71 | CYP2D6 (0.57) | METAP2MMP8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7950693 | 0.70 | LAP3 (0.72) | POLBMETAP2CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235929-B1 | SELECTIVELY INHIBITING SERINE PROTEASES, SELECTIVELY INHIBITING CYSTEINE PROTEASES, | GEORGIA TECH RESEARCH CORPORATION | 2001-05-22 | — | — | US | disclosed |
| US-5763576-A | Tetrapeptide α-ketoamides | GEORGIA TECH RESEARCH CORP. (US) | 1998-06-09 | — | — | US | disclosed |