Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 11/20 | 0.45 |
| ▸ | CTSL | P07711 | 10/20 | 0.45 |
| ▸ | CTSB | P07858 | 7/20 | 0.45 |
| ▸ | CTSK | P43235 | 5/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18103765 | 0.92 | KYNU (0.51) | KYNUCTSSCTSLCTSBCTSK | |
| SCHEMBL18103764 | 0.92 | KYNU (0.51) | KYNUCTSSCTSLCTSBCTSK | |
| SCHEMBL7922945 | 0.90 | KLK7 (0.51) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7928203 | 0.86 | CTSS (0.49) | KYNUCTSSCTSLCTSBCTSK | |
| SCHEMBL18103837 | 0.86 | CASP1 (0.53) | KYNUCTSSCTSLCTSBCTSK | |
| SCHEMBL6812701 | 0.80 | CTSS (0.52) | KYNUCTSSCTSLCTSBCTSK | |
| SCHEMBL25491977 | 0.78 | MMP9 (0.52) | KYNUCTSSCTSLCTSBCTSK | |
| SCHEMBL755795 | 0.78 | MMP9 (0.52) | KYNUCTSSCTSLCTSBCTSK | |
| SCHEMBL15996601 | 0.77 | ALDH1A1 (0.55) | KYNUCTSSCTSLCTSBCTSK | |
| SCHEMBL890103 | 0.77 | ALDH1A1 (0.55) | KYNUCTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235929-B1 | SELECTIVELY INHIBITING SERINE PROTEASES, SELECTIVELY INHIBITING CYSTEINE PROTEASES, | GEORGIA TECH RESEARCH CORPORATION | 2001-05-22 | — | — | US | disclosed |
| US-5763576-A | Tetrapeptide α-ketoamides | GEORGIA TECH RESEARCH CORP. (US) | 1998-06-09 | — | — | US | disclosed |