Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920761 | 0.91 | NPC1 (0.54) | DHODHNPC1RAB9AHSD17B10PTGS2 | |
| SCHEMBL18787586 | 0.91 | PTGS2 (0.53) | DHODHNPC1RAB9AHSD17B10PTGS2 | |
| SCHEMBL2782868 | 0.83 | MAPK14 (0.54) | DHODHNPC1RAB9AHSD17B10MAPT | |
| SCHEMBL7928875 | 0.82 | PTGS2 (0.49) | DHODHNPC1RAB9AHSD17B10PTGS2 | |
| SCHEMBL378949 | 0.81 | SMN1; SMN2 (0.62) | DHODHNPC1RAB9AHSD17B10MAPT | |
| SCHEMBL7926077 | 0.80 | EGFR (0.58) | DHODHNPC1RAB9AHSD17B10PTGS2 | |
| SCHEMBL1920755 | 0.79 | NPC1 (0.60) | DHODHNPC1RAB9AHSD17B10MAPT | |
| SCHEMBL2781010 | 0.77 | RAB9A (0.59) | DHODHNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14028296 | 0.76 | HIF1A (0.57) | DHODHNPC1RAB9AHSD17B10PTGS2 | |
| SCHEMBL24778135 | 0.75 | MAPT (0.46) | DHODHNPC1RAB9AHSD17B10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228547-B1 | CHARGE TRANSFER COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-05-08 | — | — | US | disclosed |