SCHEMBL1920761

SCHEMBL1920761

c1ccc(Nc2ccc3c(c2)OCO3)c(Nc2ccc3c(c2)OCO3)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.54
RAB9A P51151 7/20 0.54
ALDH1A1 P00352 4/20 0.54
PKM P14618 1/20 0.54
DHODH Q02127 1/20 0.54
ALOX15 P16050 1/20 0.54
HSD17B10 Q99714 1/20 0.54
MAPK9 P45984 1/20 0.53
MAPK10 P53779 1/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
MAPT P10636 4/20 0.53
GAA P10253 2/20 0.53
MEN1 O00255 2/20 0.53
POLB P06746 2/20 0.53
KMT2A Q03164 2/20 0.53
HPGD P15428 1/20 0.53
PTGS2 P35354 2/20 0.51
LMNA P02545 1/20 0.50
EGFR P00533 1/20 0.50
NFKB1 P19838 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928874 0.91 DHODH (0.61) NPC1RAB9AALDH1A1PKMDHODH
SCHEMBL2782868 0.88 MAPK14 (0.54) NPC1RAB9AALDH1A1PKMDHODH
SCHEMBL378949 0.86 SMN1; SMN2 (0.62) NPC1RAB9AALDH1A1PKMDHODH
SCHEMBL18787586 0.85 PTGS2 (0.53) NPC1RAB9AALDH1A1PKMDHODH
SCHEMBL7926077 0.85 EGFR (0.58) NPC1RAB9AALDH1A1PKMDHODH
SCHEMBL1920755 0.84 NPC1 (0.60) NPC1RAB9AALDH1A1PKMDHODH
SCHEMBL2781010 0.82 RAB9A (0.59) NPC1RAB9AALDH1A1PKMDHODH
SCHEMBL7928875 0.81 PTGS2 (0.49) NPC1RAB9AALDH1A1PKMDHODH
SCHEMBL1921386 0.78 CLK1 (0.55) NPC1RAB9AALDH1A1PKMDHODH
SCHEMBL2783079 0.78 MAPK14 (0.54) NPC1RAB9AALDH1A1DHODHALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6228547-B1 CHARGE TRANSFER COMPOUNDS TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-05-08 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed