Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18787586 | 0.89 | PTGS2 (0.53) | PTGS2DHODHMAPK9MAPK10MAPT | |
| SCHEMBL7928874 | 0.82 | DHODH (0.61) | PTGS2DHODHMAPK9MAPK10MAPT | |
| SCHEMBL1920761 | 0.81 | NPC1 (0.54) | PTGS2DHODHMAPK9MAPK10MAPT | |
| SCHEMBL2782868 | 0.77 | MAPK14 (0.54) | DHODHMAPK9MAPK10MAPTNPC1 | |
| SCHEMBL6077288 | 0.76 | MAPT (0.52) | PTGS2KDM1AMAPTHPGDHSD17B10 | |
| SCHEMBL30350962 | 0.76 | MAPT (0.52) | PTGS2KDM1AMAPTHPGDHSD17B10 | |
| SCHEMBL24778135 | 0.74 | MAPT (0.46) | PTGS2DHODHMAPTNPC1RAB9A | |
| SCHEMBL7926077 | 0.74 | EGFR (0.58) | PTGS2DHODHADRA2AMAPTNPC1 | |
| SCHEMBL8620153 | 0.73 | TDP1 (0.48) | PTGS2MAPTHPGDHSD17B10TP53 | |
| SCHEMBL378949 | 0.72 | SMN1; SMN2 (0.62) | DHODHADRA2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228547-B1 | CHARGE TRANSFER COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-05-08 | — | — | US | disclosed |