Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667993 | 0.98 | CYP1A2 (0.41) | CYP1A2CYP2D6HPGDCYP2C19ALDH1A1 | |
| SCHEMBL30416262 | 0.79 | NOS3 (0.50) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL6547372 | 0.79 | NOS3 (0.50) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL16229861 | 0.78 | ENPP2 (0.39) | CYP1A2ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL8358341 | 0.78 | SIGMAR1 (0.50) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18323876 | 0.77 | ALDH1A1 (0.37) | CYP1A2CYP2D6HPGDCYP2C19ALDH1A1 | |
| SCHEMBL25389224 | 0.74 | GRIN2B (0.43) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL8356086 | 0.74 | NPC1 (0.41) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL7927948 | 0.72 | PTGDR2 (0.39) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL16102283 | 0.72 | ALDH1A1 (0.35) | CYP1A2HPGDALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269523-A1 | Preparation of Aminoaryl and Aminoheteroaryl Boronic Acids and Derivatives Thereof | ARCHIMICA GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269523-A1 | Preparation of Aminoaryl and Aminoheteroaryl Boronic Acids and Derivatives Thereof | BCAT1, BCAT2, AADAT | CYP1A2 787/4885CYP2D6 1012/4885HPGD 3195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.