SCHEMBL7929549

SCHEMBL7929549

Oc1c(I)cc(-c2ccccc2)cc1I

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 2/20 0.54
CRHR2 Q13324 2/20 0.54
TTR P02766 2/20 0.48
PTPN1 P18031 3/20 0.46
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
ALDH1A1 P00352 2/20 0.45
ALOX5 P09917 1/20 0.44
BACE1 P56817 1/20 0.44
AKR1C2 P52895 3/20 0.42
AKR1C1 Q04828 3/20 0.42
AKR1C4 P17516 1/20 0.42
AKR1C3 P42330 1/20 0.42
PTPN2 P17706 1/20 0.41
PTPN6 P29350 1/20 0.41
EGFR P00533 1/20 0.41
ESR2 Q92731 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19428392 0.84 TTR (0.65) TTRPTPN1ALDH1A1EGFRKDM4E
SCHEMBL18855325 0.81 TTR (0.61) TTRPTPN1ALDH1A1EGFRKDM4E
SCHEMBL11502250 0.80 PTPN1 (0.44) CRHBPCRHR2PTPN1MMP3BCL2L1
SCHEMBL8994783 0.80 ESR1 (0.62) TTRMMP3BCL2L1ALOX5ESR2
SCHEMBL24729298 0.79 ALDH1A1 (0.50) CRHBPCRHR2MMP3BCL2L1ALDH1A1
SCHEMBL18643105 0.79 PTPN1 (0.54) CRHBPCRHR2PTPN1BCL2L1PTPN2
SCHEMBL22717152 0.77 ALDH1A1 (0.47) CRHBPCRHR2PTPN1MMP3BCL2L1
SCHEMBL326717 0.76 ALOX5 (0.64) MMP3BCL2L1ALDH1A1ALOX5BACE1
SCHEMBL8773702 0.76 RXRA (0.60) BCL2L1EGFRKDM4ELMNAHSD17B10
SCHEMBL411275 0.75 CA1 (0.70) CRHBPCRHR2TTRPTPN1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707849-A1 USE OF DERIVATIVES OF 2,4-BISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS BOBEL246 S.L. (ES) 1996-04-24 EP claimed
WO-2025120339-A1 AMINOALKYLATED BENZOXY COMPOUNDS FOR USE IN THE TREATMENT OF CARDIAC DISORDERS Szegedi Tudományegyetem (HU) 2025-06-12 WO disclosed
EP-0707849-B1 USE OF DERIVATIVES OF 2,4-DISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS BOBEL246 S L (ES) 2001-12-19 EP disclosed
US-5558982-A High chloride (100) tabular grain emulsions with modified edge structures EASTMAN KODAK COMPANY (US) 1996-09-24 US disclosed
EP-0731378-A1 Emulsions with tabular grain major faces formed by regions of differing iodide concentrations EASTMAN KODAK COMPANY (US) 1996-09-11 EP disclosed
EP-0731379-A1 Photographic emulsions containing tabular grains with a band structure and a central grain portion of high bromide concentration EASTMAN KODAK COMPANY (US) 1996-09-11 EP disclosed
EP-0701166-A1 Grain growth process for the preparation of high bromide ultrathin tabular grain emulsions EASTMAN KODAK COMPANY (US) 1996-03-13 EP disclosed
EP-0694809-A1 A novel class of grain growth modifiers for the preparation of high chloride (111) tabular grain emulsions (II) EASTMAN KODAK COMPANY (US) 1996-01-31 EP disclosed
EP-0670514-A2 High chloride (100) tabular grain emulsions with modified edge structures EASTMAN KODAK COMPANY (US) 1995-09-06 EP disclosed