Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 4/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033529 | 0.77 | NR4A2 (0.54) | FTOSRCEGFRKDM4EHPGD | |
| SCHEMBL3885361 | 0.76 | GPR3 (0.52) | FTOKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL3875323 | 0.73 | GPR3 (0.48) | FTOKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL986790 | 0.73 | TSHR (0.48) | FTOSRCEGFRKDM4EHPGD | |
| SCHEMBL6976466 | 0.73 | NR4A2 (0.43) | FTOKDM4EHPGDALDH1A1LMNA | |
| SCHEMBL17122553 | 0.73 | KDM4E (0.53) | SRCEGFRKDM4EHPGDALDH1A1 | |
| SCHEMBL161776 | 0.71 | LMNA (0.56) | FTOKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL19249104 | 0.71 | KDM4E (0.53) | SRCEGFRKDM4EHPGDALDH1A1 | |
| SCHEMBL2215785 | 0.70 | GABRP (0.52) | KDM4EALDH1A1PABPC1EIF4HGABRP | |
| SCHEMBL5964412 | 0.70 | ALKBH5 (0.63) | FTOEGFRKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248264-B1 | WINDOWS OR EYEGLASS/SUNGLASS LENSES HAVING GOOD DARKENING AND LIGHTENING PERFORMANCE WITH HIGH OPTICAL DENSITY | JAMES ROBINSON LIMITED (GB) | 2001-06-19 | — | — | US | disclosed |
| EP-0971914-A2 | NEUTRAL COLOURING PHOTOCHROMIC 2$i(H)-NAPHTHO 1,2-$i(b)]PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042693-A2 | NEUTRAL COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LIMITED (GB) | 1998-10-01 | — | — | WO | disclosed |