SCHEMBL7932608

SCHEMBL7932608

C=C1CC(=O)N(c2ccc(Cc3ccc(N4C(=O)CC(=C)C4=O)cc3)cc2)C1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.48
FAAH O00519 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 2/20 0.39
KCNH2 Q12809 1/20 0.39
GAA P10253 4/20 0.38
TLR9 Q9NR96 2/20 0.38
PKM P14618 1/20 0.38
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
STAT3 P40763 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TRIP13 Q15645 2/20 0.35
MAPT P10636 1/20 0.34
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237914 0.89 GAA (0.44) MGLLFAAHSMN1; SMN2ALDH1A1LMNA
SCHEMBL24741191 0.83 MGLL (0.54) MGLLFAAHALDH1A1LMNAGAA
SCHEMBL12317338 0.81 TRIM24 (0.42) SMN1; SMN2ALDH1A1GAATLR9PKM
SCHEMBL4894350 0.80 MEN1 (0.54) MGLLSMN1; SMN2ALDH1A1LMNAMEN1
SCHEMBL2983688 0.80 GAA (0.57) MGLLSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL4443303 0.80 MGLL (0.56) MGLLFAAHALDH1A1LMNAPKM
SCHEMBL225820 0.79 GAA (0.58) MGLLALDH1A1GAATLR9PKM
SCHEMBL24741188 0.77 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1LMNAGAATLR9
SCHEMBL22728447 0.76 BCHE (0.47) SMN1; SMN2ALDH1A1LMNAKCNH2GAA
SCHEMBL12268781 0.75 ADAM17 (0.50) SMN1; SMN2ALDH1A1GAATLR9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KANEKA CORPORATION (JP) 2023-11-16 US disclosed
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KANEKA CORPORATION (JP) 2023-11-16 US disclosed
EP-0800551-B1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL NV (NL) 2001-06-13 EP disclosed
US-5844049-A Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds AKZO NOBEL NV (NL) 1998-12-01 US disclosed
EP-0800551-A1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS Akzo Nobel N.V. (NL) 1997-10-15 EP disclosed
WO-1996020246-A1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL N.V. (NL) 1996-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KDM5C, DHX15, KDM5A MGLL 4346/4885FAAH 756/4885SMN1; SMN2 2769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.