Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020563 | 0.85 | HTR1A (0.35) | IDO1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7935365 | 0.83 | LTA4H (0.32) | IDO1MAOBNPC1RAB9AKMT2A | |
| SCHEMBL8013011 | 0.78 | CHRM2 (0.31) | ALDH1A1 | |
| SCHEMBL7944942 | 0.76 | RET (0.35) | SCN3AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7944450 | 0.75 | ALOX12 (0.45) | — | |
| Hydrochloric Acid SCHEMBL7946351 | 0.75 | — | — | |
| SCHEMBL7945043 | 0.69 | AADAT (0.40) | — | |
| SCHEMBL10403793 | 0.66 | HTR2A (0.30) | — | |
| SCHEMBL8013738 | 0.66 | MGLL (0.36) | ALDH1A1NPC1RAB9A | |
| SCHEMBL2335384 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075144-A | ABILITY TO INHIBIT ACETYLCHOLINESTERASE; TREATS ALZHEIMER,S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 2000-06-13 | — | — | US | claimed |
| US-6248750-B1 | CHOLINERGIC FUNCTION AGONISTS FOR MEMORY ENHANCEMENT | HOECHST ROUSSEL PHARMACEUTICALS | 2001-06-19 | — | — | US | disclosed |
| US-6075144-A | ABILITY TO INHIBIT ACETYLCHOLINESTERASE; TREATS ALZHEIMER,S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 2000-06-13 | — | — | US | disclosed |