Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938605 | 0.92 | KMT2A (0.40) | KMT2AGAAATMALDH1A1MEN1 | |
| SCHEMBL8153591 | 0.88 | GAA (0.36) | KMT2AGAAATMALDH1A1MEN1 | |
| SCHEMBL7932818 | 0.82 | MAPT (0.47) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL7926378 | 0.81 | ALDH1A1 (0.43) | KMT2AGAAATMALDH1A1MEN1 | |
| SCHEMBL7926376 | 0.80 | POLB (0.46) | KMT2AGAAATMMEN1CYP1A2 | |
| SCHEMBL6794821 | 0.80 | PPOX (0.44) | KMT2AGAAATMALDH1A1MAPK1 | |
| SCHEMBL7935713 | 0.79 | NPBWR1 (0.34) | KMT2AGAAATMALDH1A1MEN1 | |
| SCHEMBL7532202 | 0.77 | PPOX (0.44) | KMT2AGAAATMMEN1CYP1A2 | |
| SCHEMBL7020290 | 0.74 | BCAT1 (0.37) | KMT2AGAAATMBLMCHRM5 | |
| SCHEMBL5388413 | 0.73 | GAA (0.37) | KMT2AGAAATMALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303543-B1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-10-16 | — | — | US | disclosed |
| US-6121201-A | HETEROARYL SUBSTITUTED HALO-PYRAZOLE SUBSTITUTED DIARYL ETHERS OR THIOETHERS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-09-19 | — | — | US | disclosed |