Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944622 | 0.89 | GPR3 (0.34) | GPR3HTR2A | |
| SCHEMBL7542646 | 0.88 | GPR3 (0.34) | GPR3NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL30084515 | 0.87 | PTPN1 (0.34) | — | |
| SCHEMBL20996282 | 0.87 | PTPN1 (0.34) | — | |
| SCHEMBL7928077 | 0.85 | — | — | |
| SCHEMBL20996271 | 0.85 | PTPN1 (0.33) | — | |
| SCHEMBL21029022 | 0.84 | MEN1 (0.33) | GPR3NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL20996628 | 0.84 | GPR3 (0.32) | GPR3NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL30307362 | 0.84 | GPR3 (0.32) | GPR3NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL20996234 | 0.81 | L3MBTL1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232256-B1 | CONTACTING A CYCLOALKADIENYL COMPOUND, A TRANSITION METAL AMIDE, AN ALUMINOXANE, AND OPTIONALLY A SOLID SUPPORT | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2001-05-15 | — | — | US | disclosed |
| EP-0933383-A1 | Catalyst composition for the polymerization of olefins | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-08-04 | — | — | EP | disclosed |