SCHEMBL7944622

SCHEMBL7944622

CC1=CC([Si](C)(C)C2c3ccccc3-c3ccccc32)c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.34
HTR2A P28223 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7936607 0.89 GPR3 (0.34) GPR3HTR2A
SCHEMBL7542646 0.81 GPR3 (0.34) GPR3HTR2A
SCHEMBL7544944 0.78 ACHE (0.33) GPR3HTR2A
SCHEMBL5175634 0.78 GPR3 (0.46) GPR3HTR2APOLB
SCHEMBL30307362 0.78 GPR3 (0.32) GPR3
SCHEMBL21029022 0.78 MEN1 (0.33) GPR3POLB
SCHEMBL20996628 0.78 GPR3 (0.32) GPR3
SCHEMBL20996282 0.77 PTPN1 (0.34)
SCHEMBL30084515 0.77 PTPN1 (0.34)
SCHEMBL20996271 0.76 PTPN1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6297333-B1 METALLOCENE TRANSITION METAL COMPOUND HAVING AN INDENYL GROUP AND A FLUORENYL GROUP AS LIGANDS, SPECIFIC SUBSTITUENT ON A SPECIFIC POSITION OF THE INDENYL GROUP GIVES HIGH MOLECULAR WEIGHT AND HIGH ACTIVITY MITSUI CHEMICALS INC (JP) 2001-10-02 US disclosed
US-6004897-A TRANSITION METAL INDENE-FLUORINE COMPLEX COORDINATION CATALYST WITH ORGANOALUMINUM AND ALUMOXANE COMPOUNDS MITSUI CHEMICALS, INC. (JP) 1999-12-21 US disclosed
EP-0754698-A2 An olefin polymerization catalyst and a process for preparing olefin polymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-01-22 EP disclosed