SCHEMBL30307362

SCHEMBL30307362

CC1=CC([Si](C)(C)Cl)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.32
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
SLC22A2 O15244 1/20 0.30
SLC22A3 O75751 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20996628 1.00 GPR3 (0.32) GPR3NPC1CASP3RAB9ASMN1; SMN2
SCHEMBL7936607 0.84 GPR3 (0.34) GPR3NPC1CASP3RAB9ASMN1; SMN2
SCHEMBL7542646 0.84 GPR3 (0.34) GPR3NPC1CASP3RAB9ASMN1; SMN2
SCHEMBL21029022 0.81 MEN1 (0.33) GPR3NPC1CASP3RAB9ASMN1; SMN2
SCHEMBL7944622 0.78 GPR3 (0.34) GPR3
SCHEMBL20996229 0.77 PTPN1 (0.37)
SCHEMBL30084521 0.77 PTPN1 (0.37)
SCHEMBL7928077 0.75
SCHEMBL7632634 0.74
SCHEMBL20920183 0.74 HTR6 (0.33) NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111406078-B Catalyst for preparing polyethylene with broad bimodal molecular weight distribution 埃克森美孚化学专利公司 2023-03-10 CN disclosed