Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17590071 | 0.88 | MAPT (0.50) | GPR119MAPTLMNAALDH1A1NPC1 | |
| SCHEMBL2056118 | 0.81 | GPR119 (0.77) | GPR119MEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL7932466 | 0.79 | PANK3 (0.46) | GPR119MEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL21241225 | 0.77 | GRIN2D (0.42) | GPR119MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL17550836 | 0.77 | TRPC6 (0.44) | GPR119MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5231173 | 0.77 | GPR119 (0.70) | GPR119MEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL5573222 | 0.73 | MAPT (0.76) | GPR119MEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL3414344 | 0.73 | ADRB1 (0.70) | MEN1KMT2ASMN1; SMN2AKR1C3MAPT | |
| SCHEMBL7105773 | 0.73 | ADRB1 (0.70) | MEN1KMT2ASMN1; SMN2AKR1C3MAPT | |
| SCHEMBL10063748 | 0.73 | ADRB1 (0.70) | MEN1KMT2ASMN1; SMN2AKR1C3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030967-A1 | 4-ARYLOXYQUINOLIN-2(1H)-ONES AS MTOR KINASE AND PI3 KINASE INHIBITORS, FOR USE AS ANTI-CANCER AGENTS | WYETH LLC (US) | 2010-03-18 | — | — | WO | disclosed |