Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941960 | 0.86 | ADAM17 (0.33) | — | |
| SCHEMBL7937958 | 0.85 | P2RX3 (0.31) | — | |
| SCHEMBL7940268 | 0.84 | P2RX3 (0.30) | — | |
| SCHEMBL7928806 | 0.84 | P2RX3 (0.34) | — | |
| SCHEMBL8107435 | 0.82 | KMT2A (0.31) | — | |
| SCHEMBL8111767 | 0.79 | GAA (0.33) | SMN1; SMN2 | |
| SCHEMBL6943250 | 0.75 | ADAM17 (0.50) | SMN1; SMN2HPGDGRIK1GRIK2 | |
| SCHEMBL7940265 | 0.74 | GAA (0.33) | SMN1; SMN2 | |
| SCHEMBL6944673 | 0.74 | ADAM17 (0.46) | SMN1; SMN2HPGDCACNA1BMAPTGRIK1 | |
| SCHEMBL7940281 | 0.74 | CCNA2 (0.31) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235787-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-05-22 | — | — | US | disclosed |