Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941960 | 0.87 | ADAM17 (0.33) | KMT2AADAM17 | |
| SCHEMBL7937958 | 0.86 | P2RX3 (0.31) | ADAM17 | |
| SCHEMBL7928806 | 0.86 | P2RX3 (0.34) | ADAM17 | |
| SCHEMBL7940268 | 0.85 | P2RX3 (0.30) | — | |
| SCHEMBL7937824 | 0.82 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL8111767 | 0.81 | GAA (0.33) | — | |
| SCHEMBL7940265 | 0.76 | GAA (0.33) | — | |
| SCHEMBL7940281 | 0.75 | CCNA2 (0.31) | — | |
| SCHEMBL6944688 | 0.75 | P2RX3 (0.31) | — | |
| SCHEMBL6943519 | 0.74 | ADAM17 (0.53) | KMT2AADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999001428-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-14 | — | — | WO | disclosed |