Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941960 | 0.88 | ADAM17 (0.33) | P2RX3 | |
| SCHEMBL7937958 | 0.87 | P2RX3 (0.31) | P2RX3 | |
| SCHEMBL7928806 | 0.86 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL8107435 | 0.85 | KMT2A (0.31) | — | |
| SCHEMBL7937824 | 0.84 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL8111767 | 0.81 | GAA (0.33) | — | |
| SCHEMBL7940281 | 0.77 | CCNA2 (0.31) | P2RX3 | |
| SCHEMBL6944688 | 0.77 | P2RX3 (0.31) | P2RX3 | |
| SCHEMBL7940265 | 0.77 | GAA (0.33) | — | |
| SCHEMBL7933428 | 0.75 | P2RX3 (0.33) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235787-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-05-22 | — | — | US | disclosed |