Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941960 | 0.78 | ADAM17 (0.33) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL7937958 | 0.77 | P2RX3 (0.31) | P2RX3 | |
| SCHEMBL7940268 | 0.77 | P2RX3 (0.30) | P2RX3 | |
| SCHEMBL7928806 | 0.76 | P2RX3 (0.34) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL8107435 | 0.75 | KMT2A (0.31) | — | |
| SCHEMBL7940275 | 0.75 | CCNA2 (0.31) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL7937824 | 0.74 | SMN1; SMN2 (0.33) | HPGD | |
| SCHEMBL8111767 | 0.73 | GAA (0.33) | — | |
| SCHEMBL7940265 | 0.72 | GAA (0.33) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL6944688 | 0.72 | P2RX3 (0.31) | CCNA2CDK2CCNA1CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235787-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-05-22 | — | — | US | disclosed |