Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969063 | 0.94 | CYP2D6 (0.42) | POLBKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL7937735 | 0.86 | KMT2A (0.41) | CYP2C9CYP2C19POLBALDH1A1KMT2A | |
| SCHEMBL7951892 | 0.86 | POLB (0.39) | POLBALDH1A1MAPK1HPGD | |
| SCHEMBL7993224 | 0.85 | MEN1 (0.42) | CYP2C9CYP2C19POLBLMNAKDM4E | |
| SCHEMBL7944071 | 0.84 | HTT (0.40) | POLBALDH1A1HPGDMMP2 | |
| SCHEMBL7948016 | 0.83 | POLB (0.38) | CYP2C19POLBKDM4EALDH1A1MAPT | |
| SCHEMBL7945520 | 0.83 | NPC1 (0.39) | CYP2C19POLBKDM4EALDH1A1MAPT | |
| SCHEMBL7982206 | 0.82 | POLB (0.36) | POLBALDH1A1KMT2AHPGDMMP2 | |
| SCHEMBL7947094 | 0.82 | POLB (0.37) | CYP2C19POLBKDM4EALDH1A1MAPT | |
| SCHEMBL7946743 | 0.82 | MITF (0.45) | CYP2C9CYP2C19POLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |