Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944575 | 0.85 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1KCNH2SLC6A2SLC6A4 | |
| SCHEMBL7947322 | 0.82 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1 | |
| SCHEMBL7986076 | 0.82 | HDAC1 (0.36) | ALDH1A1KCNH2SLC6A2SLC6A4 | |
| SCHEMBL7946271 | 0.81 | ATM (0.43) | ALDH1A1KCNH2 | |
| SCHEMBL7938073 | 0.80 | HRH3 (0.37) | ALDH1A1 | |
| SCHEMBL7938183 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MTNR1AKCNH2 | |
| SCHEMBL7945088 | 0.76 | HDAC1 (0.38) | ALDH1A1KCNH2SLC6A2SLC6A4 | |
| SCHEMBL7969135 | 0.75 | BCHE (0.38) | MTNR1AKCNH2SLC6A2SLC6A4 | |
| SCHEMBL7944087 | 0.75 | BCHE (0.37) | KCNH2SLC6A2SLC6A4 | |
| SCHEMBL13896765 | 0.73 | MEN1 (0.41) | ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |