Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945088 | 0.89 | HDAC1 (0.38) | HDAC1HDAC6KCNH2CYP2D6SLC6A2 | |
| SCHEMBL7944087 | 0.88 | BCHE (0.37) | HDAC1HDAC6KCNH2CYP2D6SLC6A2 | |
| SCHEMBL7944573 | 0.86 | TDP1 (0.37) | KCNH2CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7980536 | 0.85 | PTGDR2 (0.35) | HDAC1HDAC6SLC6A2SLC6A4PKM | |
| SCHEMBL7969135 | 0.83 | BCHE (0.38) | KCNH2CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7938770 | 0.82 | L3MBTL1 (0.38) | KCNH2SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL7971749 | 0.80 | KDM4E (0.35) | KCNH2EPHX1PTGDR2EPHX2ALDH1A1 | |
| SCHEMBL7947592 | 0.80 | RAB9A (0.36) | KCNH2CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7947140 | 0.80 | PKM (0.37) | HDAC1HDAC6CYP2D6PKMF2 | |
| SCHEMBL7938183 | 0.77 | ALDH1A1 (0.37) | KCNH2ALDH1A1F2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |