Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986076 | 0.83 | HDAC1 (0.36) | BCHESLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7948614 | 0.82 | POLB (0.40) | NPC1RAB9A | |
| SCHEMBL7946271 | 0.81 | ATM (0.43) | KCNH2NPC1RAB9A | |
| SCHEMBL7945088 | 0.81 | HDAC1 (0.38) | BCHESLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7944087 | 0.80 | BCHE (0.37) | BCHESLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7938183 | 0.80 | ALDH1A1 (0.37) | KCNH2ACKR3F2PRMT5WDR77 | |
| SCHEMBL7944573 | 0.80 | TDP1 (0.37) | BCHESLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL13896768 | 0.79 | TACR1 (0.44) | NPC1RAB9A | |
| SCHEMBL7945174 | 0.77 | HTR2A (0.40) | BCHECYP2D6RAB9A | |
| SCHEMBL7947592 | 0.76 | RAB9A (0.36) | BCHESLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |