Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MB | P02144 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945326 | 0.82 | KMT2A (0.41) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL7939128 | 0.81 | LMNA (0.52) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL7939052 | 0.80 | ALDH1A1 (0.49) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7947441 | 0.79 | SMN1; SMN2 (0.47) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL6814332 | 0.72 | ALDH1A1 (0.56) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL7945458 | 0.71 | MAPT (0.48) | KMT2AMEN1SMN1; SMN2LMNANPC1 | |
| SCHEMBL8030141 | 0.69 | ALDH1A1 (0.41) | KMT2AMEN1LMNAPOLBNPC1 | |
| SCHEMBL13941263 | 0.67 | TSHR (0.58) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL7113343 | 0.66 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2LMNANPC1 | |
| SCHEMBL8027473 | 0.66 | ALDH1A1 (0.47) | KMT2AMEN1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |