Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19837655 | 0.83 | DRD2 (0.90) | DRD2DRD3AKR1C3ALOX15HDAC1 | |
| SCHEMBL19837643 | 0.83 | DRD2 (0.90) | DRD2DRD3AKR1C3ALOX15HDAC1 | |
| SCHEMBL74104 | 0.78 | DRD2 (1.00) | DRD2DRD3AKR1C3ALOX15HDAC1 | |
| SCHEMBL7940514 | 0.78 | CA12 (0.61) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL7948708 | 0.75 | USP2 (0.56) | PLA2G7GPR84USP2NAAAKDM4E | |
| SCHEMBL7938107 | 0.74 | CDC25B (0.46) | AKR1C3KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11131822 | 0.74 | NAAA (0.61) | USP2ALOX15NAAAKDM4EALDH1A1 | |
| SCHEMBL10435868 | 0.74 | NAAA (0.61) | PLA2G7USP2HDAC1HDAC2HDAC3 | |
| SCHEMBL27550290 | 0.74 | AKR1C3 (0.86) | DRD2DRD3AKR1C3HDAC1HDAC2 | |
| SCHEMBL7952048 | 0.74 | RAB9A (0.61) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513295-B2 | Viral and fungal inhibitors | GEORGETOWN UNIVERSITY (US) | 2013-08-20 | — | — | US | disclosed |
| US-8513295-B2 | Viral and fungal inhibitors | GEORGETOWN UNIVERSITY (US) | 2013-08-20 | — | — | US | disclosed |
| US-20110301208-A1 | VIRAL AND FUNGAL INHIBITORS | WICHITA STATE UNIVERSITY (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301208-A1 | VIRAL AND FUNGAL INHIBITORS | WICHITA STATE UNIVERSITY (US) | 2011-12-08 | — | — | US | disclosed |
| WO-2010039534-A2 | VIRAL AND FUNGAL INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301208-A1 | VIRAL AND FUNGAL INHIBITORS | HAVCR2, ZC3HAV1, ERG28 | DRD2 4802/4885DRD3 4620/4885PLA2G7 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.