Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350220 | 1.00 | CYP3A4 (0.31) | CYP3A4 | |
| SCHEMBL7352238 | 0.80 | CYP3A4 (0.36) | CYP3A4 | |
| SCHEMBL7355758 | 0.79 | CA2 (0.41) | — | |
| SCHEMBL7351472 | 0.79 | DRD2 (0.34) | CYP3A4 | |
| SCHEMBL7350303 | 0.78 | CYP3A4 (0.33) | CYP3A4 | |
| SCHEMBL2122378 | 0.70 | PDE4A (0.35) | — | |
| SCHEMBL7376695 | 0.69 | KMT2A (0.47) | CYP3A4 | |
| SCHEMBL7354632 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL16472640 | 0.64 | CYP2A6 (0.40) | CYP3A4 | |
| SCHEMBL7259704 | 0.63 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |