Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352238 | 0.90 | CYP3A4 (0.36) | CYP3A4CA2CA12CFDDRD2 | |
| SCHEMBL7351472 | 0.80 | DRD2 (0.34) | CYP3A4CA2DRD2DRD4DRD3 | |
| SCHEMBL7356228 | 0.78 | TUBB4A (0.42) | CYP3A4CA2TRPA1 | |
| SCHEMBL7355758 | 0.78 | CA2 (0.41) | CA2CA12DRD2DRD4DRD3 | |
| SCHEMBL7940562 | 0.78 | CYP3A4 (0.31) | CYP3A4 | |
| SCHEMBL7350220 | 0.78 | CYP3A4 (0.31) | CYP3A4 | |
| SCHEMBL2122378 | 0.74 | PDE4A (0.35) | DRD2DRD4DRD3 | |
| SCHEMBL7357481 | 0.72 | CA6 (0.37) | CA2CA1 | |
| SCHEMBL7376695 | 0.70 | KMT2A (0.47) | CYP3A4CA2CA1 | |
| SCHEMBL7354632 | 0.69 | ALDH1A1 (0.34) | CA2TRPA1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-5877190-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |